Tag: 苏州桑拿

Cheap PR stunt backfires on online agents

Cheap PR stunt backfires on online agents

first_imgHome » News » Agencies & People » Cheap PR stunt backfires on online agents Cheap PR stunt backfires on online agents9th October 20150695 Views A PR stunt in the form of a slow drive funeral procession through the streets of London, supposedly marking the death of the high street estate agency sector, backfired on the online agency who staged it, confirming that their unprofessional and cheap marketing methods bring their own business nothing but damage.Founder and CEO of eMoov.co.uk, Russell Quirk, branded the stunt “dead wrong” and while he believes that the property industry “needs a kick”, he insisted that online agents should aim to “improve” the home buying and selling experience, and “not to ‘kill’ estate agents”.Russell (left) said “They clearly have their own view on marketing strategy and this particular style may work for them. But the business of selling someone’s family home with care and at the best price is a very serious business.”Adam Male, Founder of Urban.co.uk, felt that the PR stunt was “effective” but insisted that “it’s in no way the end of the high street.”He commented, “I believe both online and traditional agency has a place in the industry. Much like John Lewis and Thomson Holidays have proven over the last five years, it’s achievable to have a successful high street operation, complemented by a great online strategy, that is what high street agents are yet to do. Until someone gets that right, online agents will continue to get huge traction and take market share from their high street cousins.”Paul Smith, CEO at haart estate agents, agreed that the traditional high street estate agent is still “alive and kicking.”Smith said, “For sellers buying a home finding a buyer is just the first step. Property chains are precarious by nature and if one buyer or seller has a wobble or gets cold feet it doesn’t usually just influence one person or family but a whole swathe of people.It requires a skilled and experienced traditional estate agent with excellent negotiation skills and an intimate knowledge of local market conditions to hold the chain together and their expertise could even help achieve a higher price.”PR stunt online agent cheap marketing methods cheap PR stunt death of the high street 2015-10-09The Negotiator Related articles Laptops donated by Hunters in memory of murdered York estate agent28th April 2021 Your Move parent group posts extraordinary profits surge28th April 2021 TPFG boss: Why we’ve joined rival LSL’s mortgage network27th April 2021What’s your opinion? Cancel replyYou must be logged in to post a comment.Please note: This is a site for professional discussion. Comments will carry your full name and company.This site uses Akismet to reduce spam. Learn how your comment data is processed.last_img read more

The cellular origin of fibrosis

The cellular origin of fibrosis

first_imgHarvard Stem Cell Institute scientists at Brigham and Women’s Hospital say they have found the cellular origin of the tissue scarring caused by organ damage associated with diabetes, lung disease, high blood pressure, kidney disease, and other conditions.The buildup of scar tissue, known as fibrosis, has a number of consequences, including inflammation and reduced blood and oxygen delivery to the organ. Long term, the scar tissue can lead to organ failure and sometimes eventually death. It is estimated that fibrosis contributes to 45 percent of all deaths in the developed world.The researchers, led by Benjamin Humphreys, found that in mice, a rare population of stem cells located outside of blood vessels become myofibroblast cells that secrete proteins that cause scar tissue. Killing these stem cells prevents the deadly complications of fibrosis, the researchers report today in the journal Cell Stem Cell online. Rafael Kramann, a postdoctoral fellow in Humphreys’ lab, is the first author on the paper.“Under normal circumstances, myofibroblasts stimulate wound healing, but when there’s an ongoing injury to an organ [such as the liver of a hepatitis C patient, the heart of a patient with high blood pressure, or the kidney of a patient with diabetes], these proteins clog up normal functioning,” said Humphreys, a Harvard Medical School associate professor at the Brigham, who leads the Harvard Stem Cell Institute Kidney Program.The researchers are now in discussions with a pharmaceutical firm about screening for drugs that might target and shut off these fibrosis-causing stem cells in cases of chronic organ disease. The idea of using the stem cells as targets for drug discovery began with the formation — by Humphreys, Kramann, and Derek DiRocco — of MatriTarg Laboratories, the startup that won the 2013 Harvard Deans’ Health and Life Sciences Challenge.“We wanted to know if eradication of this very small population of stem cells would improve organ function, and both kidney and heart were completely protected from developing fibrosis-related complications [such as kidney failure and heart failure],” said Humphreys, who also heads the Onco-Nephrology Program at the Dana-Farber Cancer Institute. “This provides an important proof of principle that drugs that target the stem cells could be therapeutic.”The cellular origin of kidney fibrosis has long puzzled researchers. It was unknown which kinds of stem cells form myofibroblasts, and where these stem cells are located. One long-held hypothesis was that the stem cells that give rise to myofibroblasts are found in the bone marrow, but Humphreys’ research disproves that. By tagging a specific protein called Gli1 expressed by the myofibroblast-forming stem cells, the scientists showed that the cells are found on the periphery of blood vessels, and also reside within organs.Humphreys does caution that the cell population his lab found is responsible for about 60 percent of all organ myofibroblasts, which means that they seem to be the most dominant source, but there may be other cells that also contribute to the myofibroblast population.“We haven’t disproven every hypothesis, and our results do leave room for other cells that might contribute to fibrosis,” he said.The Humphreys Lab collaborated with fellow Harvard Stem Cell Institute member Benjamin Ebert, an associate professor of medicine at Brigham and Women’s Hospital, on the work.The research was supported by the Harvard Stem Cell Institute, the National Institutes of Health, the National Institute of Diabetes and Digestive and Kidney Diseases, the American Heart Association, and the Deutsche Forschungsgemeinschaft.last_img read more

Let’s hear it for Booooth!

Let’s hear it for Booooth!

first_img22 June 2009 As anyone watching South Africa in action at the Fifa Confederations Cup has surely noticed, whenever the ball finds its way to towering Bafana Bafana defender Matthew Booth, an unusual cry goes up around the stands. To the uninitiated it might sound like the thousands of home fans are registering their displeasure at the Mamelodi Sundowns defender. After all, Booth would not be the first player to be on the receiving end of catcalls from his own fans. But as millions of spectators around the world discovered last week, the noise that greets his every intervention are not boos, but supporting cries of “Booooth!”. What was perplexing viewers even more was the fact that the man in question barely put a foot wrong in his side’s opening two games, prompting them to ask why fans would boo one of their own players when he was performing so well. It was a riddle that even South Africa coach Joel Santana had to ponder after he took over the job. “The first time I heard the shouts in the stadium, I just couldn’t understand what was going on,” the Brazilian said. “I was under the impression that the fans loved Matthew, but there they were seemingly booing him for no apparent reason.” But as the smiling Booth explained to Fifa.com, peculiar cries of encouragement are something of a tradition among football fans in the Rainbow Nation. “When Mark Fish played for Bafana Bafana, it was the same. The fans shouted ‘Fiiish! Fiiish!’, and it sounded like they were having a go at him. I’ve lost count of the number of times I’ve had to explain to foreigners that there’s nothing wrong, that people love me really.” And the dependable defender is not wrong, receiving the kind of adulation normally reserved for goalscorers and more creative players. “I think it’s got something to do with my commitment,” he continues. “The fans can see that I take games seriously. Or maybe it’s just because I look like a nice guy to them! I don’t know. You’d have to ask them.” A veteran of seven seasons in Russia before returning home, Booth is hoping to take part in his first Fifa World Cup finals next year. He came agonisingly close to making an appearance at Korea/Japan 2002, suffering a kee injury during a training session at the squad’s pre-tournament camp in Hong Kong just 10 days before the opening game. “That was very tough to take,” he recalls. “It was the only time I’ve ever had surgery in my career, and it wasn’t even that serious. It just came at the worst possible time. “That’s why I want to try and convince Joel Santana with my performances at the Confederations Cup and make sure of a place for 2010. It would mean so much to me.” Source: Fifa.comlast_img read more

Cartoon: Edge Cases

Cartoon: Edge Cases

first_imgTags:#Cartoons#web 4 Keys to a Kid-Safe App More Noise to Signal. 12 Unique Gifts for the Hard-to-Shop-for People… Related Posts rob cottingham 9 Books That Make Perfect Gifts for Industry Ex… Hard to believe it’s already been a year since I posted my farewell to Internet Explorer 6. (By “farewell” I meant “Just frickin’ die already.”)My post was prompted by the announcement that support was ending for IE6 on Google Apps; since then, IE6’s decline has accelerated, dwindling into low-single-digit percentages of browser visits (if that) on most of the sites I manage.And this week, the latest heavyweight jumped on the let’s-kill-IE6 bandwagon: Microsoft, which launched the Internet Explorer 6 Countdown site. It sets a target of reducing IE6 usage to less than 1% worldwide.“For the love of god, please stop using our product” is an unusual message, but it’s a welcome one from Redmond. I’ve already been told by one client not to bother supporting it – which is very welcome news.So if you haven’t already struck IE6’s installed base off your list of users you have to support, chances are you’ll be doing it sometime in the next few months.But don’t feel too smug. If there’s anything to the latest sensational headlines from astronomy news (and that might be a big if), we might have a whole new group of use cases to consider. 5 Outdoor Activities for Beating Office Burnoutlast_img read more

Video: Michigan Stuffs Minnesota At The 1-Yard Line, Wins The Little Brown Jug

Video: Michigan Stuffs Minnesota At The 1-Yard Line, Wins The Little Brown Jug

first_imgMichigan defensive line stuffs Minnesota at the goal line.Twitter/@ByAZunigaThe end to the Michigan-Minnesota game was not exactly a ringing endorsement of interim Gophers coach Tracy Claeys. The Gophers appeared to take the lead on a beautiful touchdown throw by Mitch Leidner to Drew Wolitarsky, but a review showed that he was down at the one yard line. Down 29-26, with a timeout left, Minnesota wasted most of its time before a Leidner incompletion on first down. The Gophers only had time for one more play, and Leidner was stuffed at the goal line by the Michigan defense.Michigan wins. https://t.co/MPy8zslh7i— Alejandro Zúñiga (@ByAZuniga) November 1, 2015Michigan had a huge win stolen a few weeks back, and today the Wolverines came out and stole a win from a very emotionally-charged Minnesota squad.last_img

Michigan Fan Gets Bicep Signed By Jim Harbaugh, Heads To Tattoo Parlor To Make It Permanent

Michigan Fan Gets Bicep Signed By Jim Harbaugh, Heads To Tattoo Parlor To Make It Permanent

first_imgJim Harbaugh looks on from the sidelines.TAMPA, FL – JANUARY 1: Head coach Jim Harbaugh of the Michigan Wolverines looks on from the sidelines during the second quarter of the Outback Bowl NCAA college football game against the South Carolina Gamecocks on January 1, 2018 at Raymond James Stadium in Tampa, Florida. (Photo by Brian Blanco/Getty Images)Most fans – even crazy college football fans – get autographs from their favorite players and coaches on jerseys, footballs, pennants, or even just plain paper. But one Michigan supporter went a different route this week at Big Ten Media Days.A Michigan fan named Gerald got his bicep signed by Wolverines head coach Jim Harbaugh – and he’s looking to make it a permanent fixture. According to Michigan, the fan headed to the tattoo parlor to get the autograph inked on. Check it out:Our man Gerald with the bicep autograph from @CoachJim4UM… Next stop, the tattoo parlor!#GoBlue pic.twitter.com/FSR3oVc1oA— Michigan Football (@umichfootball) July 26, 2016 Considering he already has the school’s ‘M’ logo on his bicep, this isn’t a huge deal – just a nice addition. It looks like he’s ready for the 2016 season to start.last_img read more